Filamentous actinobacteria are widely used as microbial cell factories to produce valuable secondary metabolites, including the vast majority of clinically relevant antimicrobial compounds.Secondary metabolites are typically encoded by large biosynthetic gene clusters, which allow for a modular approach to generating diverse compounds through recom
Racial Microaggressions and Ontological Security: Exploring the Narratives of Young Adult Migrants in Glasgow, UK
This study investigates the lived experiences of racial microaggressions faced by young adult migrants in everyday life in Glasgow, UK.The personal stories reported in this study are a direct challenge to the dominant political narrative that Scotland does not have a racism problem.When faced with this discord between narrative and reality, young a
Mapping imported malaria in Bangladesh using parasite genetic and human mobility data
For countries aiming for malaria elimination, travel of infected individuals between endemic areas undermines local interventions.Quantifying parasite importation has therefore become a priority for national control programs.We analyzed epidemiological surveillance data, travel surveys, parasite genetic data, and anonymized mobile phone data to mea
Phylogenetic analyses place the monotypic Dryopolystichum within Lomariopsidaceae
The monotypic fern genus Dryopolystichum Copel.combines a unique edible bra and panty set assortment of characters that obscures its relationship to other ferns.Its thin-walled sporangium with a vertical and interrupted annulus, round sorus with peltate indusium, and petiole with several vascular bundles place it in suborder Polypodiineae, but more
Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast
Abstract Background N-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing properties.The systems protecting cells from HAP and related noncanonical purines in Escherichia coli include specialized deoxyribonucleoside triph